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All-trans retinoic acid-induced hypothalamus–pituitary–adrenal hyperactivity involves glucocorticoid receptor dysregulation

Clinical reports have highlighted a role for retinoids in the etiology of mood disorders. Although we had shown that recruitment of the nuclear receptor retinoic acid receptor-α (RAR-α) to corticotropin-releasing hormone (CRH) promoter is implicated in activation of the hypothalamus–pituitary–adrena...

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Detalles Bibliográficos
Autores principales: Hu, P, Liu, J, Zhao, J, Qi, X-R, Qi, C-C, Lucassen, P J, Zhou, J-N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030330/
https://www.ncbi.nlm.nih.gov/pubmed/24346134
http://dx.doi.org/10.1038/tp.2013.98