Efficient discovery of responses of proteins to compounds using active learning

BACKGROUND: Drug discovery and development has been aided by high throughput screening methods that detect compound effects on a single target. However, when using focused initial screening, undesirable secondary effects are often detected late in the development process after significant investment...

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Detalles Bibliográficos
Autores principales: Kangas, Joshua D, Naik, Armaghan W, Murphy, Robert F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030446/
https://www.ncbi.nlm.nih.gov/pubmed/24884564
http://dx.doi.org/10.1186/1471-2105-15-143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030446/
https://www.ncbi.nlm.nih.gov/pubmed/24884564
http://dx.doi.org/10.1186/1471-2105-15-143

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