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Efficient discovery of responses of proteins to compounds using active learning
BACKGROUND: Drug discovery and development has been aided by high throughput screening methods that detect compound effects on a single target. However, when using focused initial screening, undesirable secondary effects are often detected late in the development process after significant investment...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030446/ https://www.ncbi.nlm.nih.gov/pubmed/24884564 http://dx.doi.org/10.1186/1471-2105-15-143 |