Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells

Ring chromosomes are structural aberrations commonly associated with birth defects, mental disabilities, and growth retardation(1,2). Rings form upon fusion of the long and short arms of a chromosome, sometimes associated with large terminal deletions(2). Due to the severity of these large-scale abe...

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Detalles Bibliográficos
Autores principales: Bershteyn, Marina, Hayashi, Yohei, Desachy, Guillaume, Hsiao, Edward C., Sami, Salma, Tsang, Kathryn M., Weiss, Lauren A., Kriegstein, Arnold R., Yamanaka, Shinya, Wynshaw-Boris, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030630/
https://www.ncbi.nlm.nih.gov/pubmed/24413397
http://dx.doi.org/10.1038/nature12923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030630/
https://www.ncbi.nlm.nih.gov/pubmed/24413397
http://dx.doi.org/10.1038/nature12923

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