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Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells
Ring chromosomes are structural aberrations commonly associated with birth defects, mental disabilities, and growth retardation(1,2). Rings form upon fusion of the long and short arms of a chromosome, sometimes associated with large terminal deletions(2). Due to the severity of these large-scale abe...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030630/ https://www.ncbi.nlm.nih.gov/pubmed/24413397 http://dx.doi.org/10.1038/nature12923 |