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Specificity Determinants for Autoproteolysis of LexA, a Key Regulator of Bacterial SOS Mutagenesis

[Image: see text] Bacteria utilize the tightly regulated stress response (SOS) pathway to respond to a variety of genotoxic agents, including antimicrobials. Activation of the SOS response is regulated by a key repressor-protease, LexA, which undergoes autoproteolysis in the setting of stress, resul...

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Detalles Bibliográficos
Autores principales: Mo, Charlie Y., Birdwell, L. Dillon, Kohli, Rahul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030785/
https://www.ncbi.nlm.nih.gov/pubmed/24779472
http://dx.doi.org/10.1021/bi500026e