DeSUMOylation Controls Insulin Exocytosis in Response to Metabolic Signals

The secretion of insulin by pancreatic islet β-cells plays a pivotal role in glucose homeostasis and diabetes. Recent work suggests an important role for SUMOylation in the control of insulin secretion from β-cells. In this paper we discuss mechanisms whereby (de)SUMOylation may control insulin rele...

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Detalles Bibliográficos
Autores principales: Vergari, Elisa, Plummer, Gregory, Dai, Xiaoqing, MacDonald, Patrick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030845/
https://www.ncbi.nlm.nih.gov/pubmed/24970137
http://dx.doi.org/10.3390/biom2020269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030845/
https://www.ncbi.nlm.nih.gov/pubmed/24970137
http://dx.doi.org/10.3390/biom2020269

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