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DeSUMOylation Controls Insulin Exocytosis in Response to Metabolic Signals
The secretion of insulin by pancreatic islet β-cells plays a pivotal role in glucose homeostasis and diabetes. Recent work suggests an important role for SUMOylation in the control of insulin secretion from β-cells. In this paper we discuss mechanisms whereby (de)SUMOylation may control insulin rele...
Autores principales: | Vergari, Elisa, Plummer, Gregory, Dai, Xiaoqing, MacDonald, Patrick E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030845/ https://www.ncbi.nlm.nih.gov/pubmed/24970137 http://dx.doi.org/10.3390/biom2020269 |
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