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Hydration-Induced Phase Separation in Amphiphilic Polymer Matrices and its Influence on Voclosporin Release
Voclosporin is a highly potent, new cyclosporine-A derivative that is currently in Phase 3 clinical trials in the USA as a potential treatment for inflammatory diseases of the eye. Voclosporin represents a number of very sparingly soluble drugs that are difficult to administer. We therefore selected...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030927/ https://www.ncbi.nlm.nih.gov/pubmed/24955746 http://dx.doi.org/10.3390/jfb3040745 |