Toxin Instability and Its Role in Toxin Translocation from the Endoplasmic Reticulum to the Cytosol

AB toxins enter a host cell by receptor-mediated endocytosis. The catalytic A chain then crosses the endosome or endoplasmic reticulum (ER) membrane to reach its cytosolic target. Dissociation of the A chain from the cell-binding B chain occurs before or during translocation to the cytosol, and only...

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Detalles Bibliográficos
Autor principal: Teter, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030972/
https://www.ncbi.nlm.nih.gov/pubmed/24970201
http://dx.doi.org/10.3390/biom3040997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030972/
https://www.ncbi.nlm.nih.gov/pubmed/24970201
http://dx.doi.org/10.3390/biom3040997

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