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Toxin Instability and Its Role in Toxin Translocation from the Endoplasmic Reticulum to the Cytosol
AB toxins enter a host cell by receptor-mediated endocytosis. The catalytic A chain then crosses the endosome or endoplasmic reticulum (ER) membrane to reach its cytosolic target. Dissociation of the A chain from the cell-binding B chain occurs before or during translocation to the cytosol, and only...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030972/ https://www.ncbi.nlm.nih.gov/pubmed/24970201 http://dx.doi.org/10.3390/biom3040997 |