Biophysical Insights into the Inhibitory Mechanism of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

HIV-1 reverse transcriptase (RT) plays a central role in HIV infection. Current United States Federal Drug Administration (USFDA)-approved antiretroviral therapies can include one of five approved non-nucleoside RT inhibitors (NNRTIs), which are potent inhibitors of RT activity. Despite their crucia...

Descripción completa

Detalles Bibliográficos
Autores principales: Schauer, Grant, Leuba, Sanford, Sluis-Cremer, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030976/
https://www.ncbi.nlm.nih.gov/pubmed/24970195
http://dx.doi.org/10.3390/biom3040889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030976/
https://www.ncbi.nlm.nih.gov/pubmed/24970195
http://dx.doi.org/10.3390/biom3040889

Ejemplares similares