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Biophysical Insights into the Inhibitory Mechanism of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

HIV-1 reverse transcriptase (RT) plays a central role in HIV infection. Current United States Federal Drug Administration (USFDA)-approved antiretroviral therapies can include one of five approved non-nucleoside RT inhibitors (NNRTIs), which are potent inhibitors of RT activity. Despite their crucia...

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Detalles Bibliográficos
Autores principales:	Schauer, Grant, Leuba, Sanford, Sluis-Cremer, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030976/ https://www.ncbi.nlm.nih.gov/pubmed/24970195 http://dx.doi.org/10.3390/biom3040889

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