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Effect of Metals on Kinetic Pathways of Amyloid-β Aggregation

Metal ions, including copper and zinc, have been implicated in the pathogenesis of Alzheimer’s disease through a variety of mechanisms including increased amyloid-β affinity and redox effects. Recent reports have demonstrated that the amyloid-β monomer does not necessarily travel through a definitiv...

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Detalles Bibliográficos
Autores principales: Hane, Francis, Leonenko, Zoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030978/
https://www.ncbi.nlm.nih.gov/pubmed/24970207
http://dx.doi.org/10.3390/biom4010101