The Role of Non-Native Interactions in the Folding of Knotted Proteins: Insights from Molecular Dynamics Simulations

For several decades, the presence of knots in naturally-occurring proteins was largely ruled out a priori for its supposed incompatibility with the efficiency and robustness of folding processes. For this very same reason, the later discovery of several unrelated families of knotted proteins motivat...

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Detalles Bibliográficos
Autores principales: Covino, Roberto, Škrbić, Tatjana, Beccara, Silvio a, Faccioli, Pietro, Micheletti, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030985/
https://www.ncbi.nlm.nih.gov/pubmed/24970203
http://dx.doi.org/10.3390/biom4010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030985/
https://www.ncbi.nlm.nih.gov/pubmed/24970203
http://dx.doi.org/10.3390/biom4010001

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