Recent Mitochondrial DNA Mutations Increase the Risk of Developing Common Late-Onset Human Diseases

Mitochondrial DNA (mtDNA) is highly polymorphic at the population level, and specific mtDNA variants affect mitochondrial function. With emerging evidence that mitochondrial mechanisms are central to common human diseases, it is plausible that mtDNA variants contribute to the “missing heritability”...

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Detalles Bibliográficos
Autores principales: Hudson, Gavin, Gomez-Duran, Aurora, Wilson, Ian J., Chinnery, Patrick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031051/
https://www.ncbi.nlm.nih.gov/pubmed/24852434
http://dx.doi.org/10.1371/journal.pgen.1004369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031051/
https://www.ncbi.nlm.nih.gov/pubmed/24852434
http://dx.doi.org/10.1371/journal.pgen.1004369

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