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Quantifying and Predicting the Effect of Exogenous Interleukin-7 on CD4(+)T Cells in HIV-1 Infection
Exogenous Interleukin-7 (IL-7), in supplement to antiretroviral therapy, leads to a substantial increase of all CD4(+) T cell subsets in HIV-1 infected patients. However, the quantitative contribution of the several potential mechanisms of action of IL-7 is unknown. We have performed a mathematical...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031052/ https://www.ncbi.nlm.nih.gov/pubmed/24853554 http://dx.doi.org/10.1371/journal.pcbi.1003630 |