Are Current Atomistic Force Fields Accurate Enough to Study Proteins in Crowded Environments?

The high concentration of macromolecules in the crowded cellular interior influences different thermodynamic and kinetic properties of proteins, including their structural stabilities, intermolecular binding affinities and enzymatic rates. Moreover, various structural biology methods, such as NMR or...

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Detalles Bibliográficos
Autores principales: Petrov, Drazen, Zagrovic, Bojan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031056/
https://www.ncbi.nlm.nih.gov/pubmed/24854339
http://dx.doi.org/10.1371/journal.pcbi.1003638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031056/
https://www.ncbi.nlm.nih.gov/pubmed/24854339
http://dx.doi.org/10.1371/journal.pcbi.1003638

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