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The Changing Geometry of a Fitness Landscape Along an Adaptive Walk

It has recently been noted that the relative prevalence of the various kinds of epistasis varies along an adaptive walk. This has been explained as a result of mean regression in NK model fitness landscapes. Here we show that this phenomenon occurs quite generally in fitness landscapes. We propose a...

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Detalles Bibliográficos
Autores principales: Greene, Devin, Crona, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031059/
https://www.ncbi.nlm.nih.gov/pubmed/24853069
http://dx.doi.org/10.1371/journal.pcbi.1003520