Aberrant DNA Methylation in ES Cells

Both mouse and human embryonic stem cells can be differentiated in vitro to produce a variety of somatic cell types. Using a new developmental tracing approach, we show that these cells are subject to massive aberrant CpG island de novo methylation that is exacerbated by differentiation in vitro. Bi...

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Detalles Bibliográficos
Autores principales: Ludwig, Guy, Nejman, Deborah, Hecht, Merav, Orlanski, Shari, Abu-Remaileh, Monther, Yanuka, Ofra, Sandler, Oded, Marx, Amichai, Roberts, Douglas, Benvenisty, Nissim, Bergman, Yehudit, Mendelsohn, Monica, Cedar, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031077/
https://www.ncbi.nlm.nih.gov/pubmed/24852222
http://dx.doi.org/10.1371/journal.pone.0096090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031077/
https://www.ncbi.nlm.nih.gov/pubmed/24852222
http://dx.doi.org/10.1371/journal.pone.0096090

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