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HCC Development Is Associated to Peripheral Insulin Resistance in a Mouse Model of NASH

NAFLD is the most common liver disease worldwide but it is the potential evolution to NASH and eventually to hepatocellular carcinoma (HCC), even in the absence of cirrhosis, that makes NAFLD of such clinical importance. Aim: we aimed to create a mouse model reproducing the pathological spectrum of...

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Detalles Bibliográficos
Autores principales: De Minicis, Samuele, Agostinelli, Laura, Rychlicki, Chiara, Sorice, Gian Pio, Saccomanno, Stefania, Candelaresi, Cinzia, Giaccari, Andrea, Trozzi, Luciano, Pierantonelli, Irene, Mingarelli, Eleonora, Marzioni, Marco, Muscogiuri, Giovanna, Gaggini, Melania, Benedetti, Antonio, Gastaldelli, Amalia, Guido, Maria, Svegliati-Baroni, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031080/
https://www.ncbi.nlm.nih.gov/pubmed/24853141
http://dx.doi.org/10.1371/journal.pone.0097136