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HCC Development Is Associated to Peripheral Insulin Resistance in a Mouse Model of NASH
NAFLD is the most common liver disease worldwide but it is the potential evolution to NASH and eventually to hepatocellular carcinoma (HCC), even in the absence of cirrhosis, that makes NAFLD of such clinical importance. Aim: we aimed to create a mouse model reproducing the pathological spectrum of...
Autores principales: | De Minicis, Samuele, Agostinelli, Laura, Rychlicki, Chiara, Sorice, Gian Pio, Saccomanno, Stefania, Candelaresi, Cinzia, Giaccari, Andrea, Trozzi, Luciano, Pierantonelli, Irene, Mingarelli, Eleonora, Marzioni, Marco, Muscogiuri, Giovanna, Gaggini, Melania, Benedetti, Antonio, Gastaldelli, Amalia, Guido, Maria, Svegliati-Baroni, Gianluca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031080/ https://www.ncbi.nlm.nih.gov/pubmed/24853141 http://dx.doi.org/10.1371/journal.pone.0097136 |
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