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Development of Peptide-Based Lineage-Specific Serology for Chronic Chagas Disease: Geographical and Clinical Distribution of Epitope Recognition

BACKGROUND: Chagas disease, caused by infection with the protozoan Trypanosoma cruzi, remains a serious public health issue in Latin America. Genetically diverse, the species is sub-divided into six lineages, known as TcI–TcVI, which have disparate geographical and ecological distributions. TcII, Tc...

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Detalles Bibliográficos
Autores principales: Bhattacharyya, Tapan, Falconar, Andrew K., Luquetti, Alejandro O., Costales, Jaime A., Grijalva, Mario J., Lewis, Michael D., Messenger, Louisa A., Tran, Trang T., Ramirez, Juan-David, Guhl, Felipe, Carrasco, Hernan J., Diosque, Patricio, Garcia, Lineth, Litvinov, Sergey V., Miles, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031129/
https://www.ncbi.nlm.nih.gov/pubmed/24852444
http://dx.doi.org/10.1371/journal.pntd.0002892