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Methylmercury Alters the Activities of Hsp90 Client Proteins, Prostaglandin E Synthase/p23 (PGES/23) and nNOS

Methylmercury (MeHg) is a persistent pollutant with known neurotoxic effects. We have previously shown that astrocytes accumulate MeHg and play a prominent role in mediating MeHg toxicity in the central nervous system (CNS) by altering glutamate signaling, generating oxidative stress, depleting glut...

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Detalles Bibliográficos
Autores principales: Caito, Samuel, Zeng, Heng, Aschner, Judy L., Aschner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031136/
https://www.ncbi.nlm.nih.gov/pubmed/24852575
http://dx.doi.org/10.1371/journal.pone.0098161