Cargando…

Network topology-based detection of differential gene regulation and regulatory switches in cell metabolism and signaling

BACKGROUND: Common approaches to pathway analysis treat pathways merely as lists of genes disregarding their topological structures, that is, ignoring the genes' interactions on which a pathway's cellular function depends. In contrast, PathWave has been developed for the analysis of high-t...

Descripción completa

Detalles Bibliográficos
Autores principales: Piro, Rosario M, Wiesberg, Stefan, Schramm, Gunnar, Rebel, Nico, Oswald, Marcus, Eils, Roland, Reinelt, Gerhard, König, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031158/
https://www.ncbi.nlm.nih.gov/pubmed/24886210
http://dx.doi.org/10.1186/1752-0509-8-56