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Network topology-based detection of differential gene regulation and regulatory switches in cell metabolism and signaling
BACKGROUND: Common approaches to pathway analysis treat pathways merely as lists of genes disregarding their topological structures, that is, ignoring the genes' interactions on which a pathway's cellular function depends. In contrast, PathWave has been developed for the analysis of high-t...
Autores principales: | Piro, Rosario M, Wiesberg, Stefan, Schramm, Gunnar, Rebel, Nico, Oswald, Marcus, Eils, Roland, Reinelt, Gerhard, König, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031158/ https://www.ncbi.nlm.nih.gov/pubmed/24886210 http://dx.doi.org/10.1186/1752-0509-8-56 |
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