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Assessment of Blood-Brain Barrier Function and the Neuroinflammatory Response in the Rat Brain by Using Cerebral Open Flow Microperfusion (cOFM)

Blood-brain barrier (BBB) impairment in systemic inflammation leads to neuroinflammation. Several factors including cytokines, chemokines and signal transduction molecules are implicated in BBB dysfunction in response to systemic inflammation. Here, we have adopted a novel in vivo technique; namely,...

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Detalles Bibliográficos
Autores principales: Ghosh, Arijit, Birngruber, Thomas, Sattler, Wolfgang, Kroath, Thomas, Ratzer, Maria, Sinner, Frank, Pieber, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031165/
https://www.ncbi.nlm.nih.gov/pubmed/24852285
http://dx.doi.org/10.1371/journal.pone.0098143