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Assessment of Blood-Brain Barrier Function and the Neuroinflammatory Response in the Rat Brain by Using Cerebral Open Flow Microperfusion (cOFM)
Blood-brain barrier (BBB) impairment in systemic inflammation leads to neuroinflammation. Several factors including cytokines, chemokines and signal transduction molecules are implicated in BBB dysfunction in response to systemic inflammation. Here, we have adopted a novel in vivo technique; namely,...
Autores principales: | Ghosh, Arijit, Birngruber, Thomas, Sattler, Wolfgang, Kroath, Thomas, Ratzer, Maria, Sinner, Frank, Pieber, Thomas R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031165/ https://www.ncbi.nlm.nih.gov/pubmed/24852285 http://dx.doi.org/10.1371/journal.pone.0098143 |
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