Pre-Clinical Characterization of Dacomitinib (PF-00299804), an Irreversible Pan-ErbB Inhibitor, Combined with Ionizing Radiation for Head and Neck Squamous Cell Carcinoma

Epidermal growth factor receptor (EGFR) is over-expressed in nearly all cases of squamous cell carcinoma of the head and neck (SCCHN), and is an important driver of disease progression. EGFR targeted therapies have demonstrated clinical benefit for SCCHN treatment. In this report, we investigated th...

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Detalles Bibliográficos
Autores principales: Williams, Justin P., Kim, Inki, Ito, Emma, Shi, Wei, Yue, Shijun, Siu, Lillian L., Waldron, John, O'Sullivan, Brian, Yip, Kenneth W., Liu, Fei-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031184/
https://www.ncbi.nlm.nih.gov/pubmed/24853121
http://dx.doi.org/10.1371/journal.pone.0098557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031184/
https://www.ncbi.nlm.nih.gov/pubmed/24853121
http://dx.doi.org/10.1371/journal.pone.0098557

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