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Identification of Nitric Oxide as an Endogenous Inhibitor of 26S Proteasomes in Vascular Endothelial Cells

The 26S proteasome plays a fundamental role in almost all eukaryotic cells, including vascular endothelial cells. However, it remains largely unknown how proteasome functionality is regulated in the vasculature. Endothelial nitric oxide (NO) synthase (eNOS)-derived NO is known to be essential to mai...

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Detalles Bibliográficos
Autores principales: Liu, Hongtao, Yu, Shujie, Zhang, Hua, Xu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031199/
https://www.ncbi.nlm.nih.gov/pubmed/24853093
http://dx.doi.org/10.1371/journal.pone.0098486