Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease

Severe acute respiratory syndrome coronavirus (SARS-CoV) encodes a papain-like protease (PLpro) with both deubiquitinating (DUB) and deISGylating activities that are proposed to counteract the post-translational modification of signaling molecules that activate the innate immune response. Here we ex...

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Detalles Bibliográficos
Autores principales: Ratia, Kiira, Kilianski, Andrew, Baez-Santos, Yahira M., Baker, Susan C., Mesecar, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031219/
https://www.ncbi.nlm.nih.gov/pubmed/24854014
http://dx.doi.org/10.1371/journal.ppat.1004113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031219/
https://www.ncbi.nlm.nih.gov/pubmed/24854014
http://dx.doi.org/10.1371/journal.ppat.1004113

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