The Cytoplasmic Tail of FPC Antagonizes the Full-Length Protein in the Regulation of mTOR Pathway

FPC (fibrocystin or polyductin) is a single transmembrane receptor-like protein, responsible for the human autosomal recessive polycystic kidney disease (ARPKD). It was recently proposed that FPC undergoes a Notch-like cleavage and subsequently the cleaved carboxy(C)-terminal fragment translocates t...

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Detalles Bibliográficos
Autores principales: Wang, Shixuan, Wu, Maoqing, Yao, Gang, Zhang, Jingjing, Zhou, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031230/
https://www.ncbi.nlm.nih.gov/pubmed/24851866
http://dx.doi.org/10.1371/journal.pone.0095630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031230/
https://www.ncbi.nlm.nih.gov/pubmed/24851866
http://dx.doi.org/10.1371/journal.pone.0095630

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