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The Cytoplasmic Tail of FPC Antagonizes the Full-Length Protein in the Regulation of mTOR Pathway
FPC (fibrocystin or polyductin) is a single transmembrane receptor-like protein, responsible for the human autosomal recessive polycystic kidney disease (ARPKD). It was recently proposed that FPC undergoes a Notch-like cleavage and subsequently the cleaved carboxy(C)-terminal fragment translocates t...
Autores principales: | Wang, Shixuan, Wu, Maoqing, Yao, Gang, Zhang, Jingjing, Zhou, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031230/ https://www.ncbi.nlm.nih.gov/pubmed/24851866 http://dx.doi.org/10.1371/journal.pone.0095630 |
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