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SMAD3 Is Associated with the Total Burden of Radiographic Osteoarthritis: The Chingford Study

BACKGROUND: A newly-described syndrome called Aneurysm-Osteoarthritis Syndrome (AOS) was recently reported. AOS presents with early onset osteoarthritis (OA) in multiple joints, together with aneurysms in major arteries, and is caused by rare mutations in SMAD3. Because of the similarity of AOS to i...

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Detalles Bibliográficos
Autores principales: Aref-Eshghi, Erfan, Zhang, Yuhua, Hart, Deborah, Valdes, Ana M., Furey, Andrew, Martin, Glynn, Sun, Guang, Rahman, Proton, Arden, Nigel, Spector, Tim D., Zhai, Guangju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031234/
https://www.ncbi.nlm.nih.gov/pubmed/24852296
http://dx.doi.org/10.1371/journal.pone.0097786