Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition

Inhibitors of matrix metalloproteinases (MMPs) have been extensively explored to treat pathologies where excessive MMP activity contributes to adverse tissue remodeling. While MMP inhibition remains a relevant therapeutic target, MMP inhibitors have not translated to clinical application due to the...

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Detalles Bibliográficos
Autores principales: Purcell, Brendan P., Lobb, David, Charati, Manoj B., Dorsey, Shauna M., Wade, Ryan J., Zellers, Kia N., Doviak, Heather, Pettaway, Sara, Logdon, Christina B., Shuman, James, Freels, Parker D., Gorman, Joseph H., Gorman, Robert C., Spinale, Francis G., Burdick, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031269/
https://www.ncbi.nlm.nih.gov/pubmed/24681647
http://dx.doi.org/10.1038/nmat3922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031269/
https://www.ncbi.nlm.nih.gov/pubmed/24681647
http://dx.doi.org/10.1038/nmat3922

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