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Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition
Inhibitors of matrix metalloproteinases (MMPs) have been extensively explored to treat pathologies where excessive MMP activity contributes to adverse tissue remodeling. While MMP inhibition remains a relevant therapeutic target, MMP inhibitors have not translated to clinical application due to the...
Autores principales: | Purcell, Brendan P., Lobb, David, Charati, Manoj B., Dorsey, Shauna M., Wade, Ryan J., Zellers, Kia N., Doviak, Heather, Pettaway, Sara, Logdon, Christina B., Shuman, James, Freels, Parker D., Gorman, Joseph H., Gorman, Robert C., Spinale, Francis G., Burdick, Jason A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031269/ https://www.ncbi.nlm.nih.gov/pubmed/24681647 http://dx.doi.org/10.1038/nmat3922 |
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