Mechanical memory and dosing influence stem cell fate

We investigated whether stem cells remember past physical signals and whether these can be exploited to dose cells mechanically. We found that the activation of the Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding domain (TAZ) as well as the pre-osteogenic transcription...

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Detalles Bibliográficos
Autores principales: Yang, Chun, Tibbitt, Mark W., Basta, Lena, Anseth, Kristi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031270/
https://www.ncbi.nlm.nih.gov/pubmed/24633344
http://dx.doi.org/10.1038/nmat3889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031270/
https://www.ncbi.nlm.nih.gov/pubmed/24633344
http://dx.doi.org/10.1038/nmat3889

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