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The effect of chemotherapeutic agents on telomere length maintenance in breast cancer cell lines

Mammalian telomeric DNA consists of tandem repeats of the sequence TTAGGG associated with a specialized set of proteins, known collectively as Shelterin. These telosomal proteins protect the ends of chromosomes against end-to-end fusion and degradation. Short telomeres in breast cancer cells confer...

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Detalles Bibliográficos
Autores principales: Motevalli, Azadeh, Yasaei, Hemad, Virmouni, Sara Anjomani, Slijepcevic, Predrag, Roberts, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031391/
https://www.ncbi.nlm.nih.gov/pubmed/24807106
http://dx.doi.org/10.1007/s10549-014-2975-x