Cargando…
The effect of chemotherapeutic agents on telomere length maintenance in breast cancer cell lines
Mammalian telomeric DNA consists of tandem repeats of the sequence TTAGGG associated with a specialized set of proteins, known collectively as Shelterin. These telosomal proteins protect the ends of chromosomes against end-to-end fusion and degradation. Short telomeres in breast cancer cells confer...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031391/ https://www.ncbi.nlm.nih.gov/pubmed/24807106 http://dx.doi.org/10.1007/s10549-014-2975-x |