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PHF8 and REST/NRSF co-occupy gene promoters to regulate proximal gene expression

Chromatin regulators play an important role in the development of human diseases. In this study, we focused on Plant Homeo Domain Finger protein 8 (PHF8), a chromatin regulator that has attracted special concern recently. PHF8 is a histone lysine demethylase ubiquitously expressed in nuclei. Mutatio...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Lin, Xueqiu, Wang, Su, Wang, Chenfei, Wang, Qixuan, Duan, Xikun, Lu, Peng, Wang, Qian, Wang, Chengyang, Liu, X. Shirley, Huang, Jinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031473/
https://www.ncbi.nlm.nih.gov/pubmed/24852203
http://dx.doi.org/10.1038/srep05008