An evolutionarily biased distribution of miRNA sites toward regulatory genes with high promoter-driven intrinsic transcriptional noise

BACKGROUND: miRNAs are a major class of regulators of gene expression in metazoans. By targeting cognate mRNAs, miRNAs are involved in regulating most, if not all, biological processes in different cell and tissue types. To better understand how this regulatory potential is allocated among different...

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Detalles Bibliográficos
Autores principales: Zare, Hossein, Khodursky, Arkady, Sartorelli, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031498/
https://www.ncbi.nlm.nih.gov/pubmed/24707827
http://dx.doi.org/10.1186/1471-2148-14-74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031498/
https://www.ncbi.nlm.nih.gov/pubmed/24707827
http://dx.doi.org/10.1186/1471-2148-14-74

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