Cargando…

New Insights into the DT40 B Cell Receptor Cluster Using a Proteomic Proximity Labeling Assay

In the vertebrate immune system, each B-lymphocyte expresses a surface IgM-class B cell receptor (BCR). When cross-linked by antigen or anti-IgM antibody, the BCR accumulates with other proteins into distinct surface clusters that activate cell signaling, division, or apoptosis. However, the molecul...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xue-Wen, Rees, Johanna S., Xue, Peng, Zhang, Hong, Hamaia, Samir W., Sanderson, Bailey, Funk, Phillip E., Farndale, Richard W., Lilley, Kathryn S., Perrett, Sarah, Jackson, Antony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031500/
https://www.ncbi.nlm.nih.gov/pubmed/24706754
http://dx.doi.org/10.1074/jbc.M113.529578