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Evolution, Mechanisms, and Applications of Intein-mediated Protein Splicing

Intein-mediated protein splicing raises questions and creates opportunities in many scientific areas. Evolutionary biologists question whether inteins are primordial enzymes or simply selfish elements, whereas biochemists seek to understand how inteins work. Synthetic chemists exploit inteins in the...

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Detalles Bibliográficos
Autores principales: Perler, Francine B., Allewell, Norma M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031505/
https://www.ncbi.nlm.nih.gov/pubmed/24695739
http://dx.doi.org/10.1074/jbc.R114.570531