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Protein Splicing: How Inteins Escape from Precursor Proteins
Inteins are nature's escape artists; they facilitate their excision from flanking polypeptides (exteins) concomitant with extein ligation to produce a mature host protein. Splicing requires sequential nucleophilic displacement reactions catalyzed by strategies similar to proteases and asparagin...
Autores principales: | Mills, Kenneth V., Johnson, Margaret A., Perler, Francine B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031507/ https://www.ncbi.nlm.nih.gov/pubmed/24695729 http://dx.doi.org/10.1074/jbc.R113.540310 |
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