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Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis
Disruption of the histone modification patterns is one of the most common features of human tumors. However, few genetic alterations in the histone modifier genes have been described in tumorigenesis. Herein we show that the histone methyltransferase SETDB1 undergoes gene amplification in non-small...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031636/ https://www.ncbi.nlm.nih.gov/pubmed/23770855 http://dx.doi.org/10.1038/onc.2013.239 |