Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

Disruption of the histone modification patterns is one of the most common features of human tumors. However, few genetic alterations in the histone modifier genes have been described in tumorigenesis. Herein we show that the histone methyltransferase SETDB1 undergoes gene amplification in non-small...

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Detalles Bibliográficos
Autores principales: Rodriguez-Paredes, M, Martinez de Paz, A, Simó-Riudalbas, L, Sayols, S, Moutinho, C, Moran, S, Villanueva, A, Vázquez-Cedeira, M, Lazo, P A, Carneiro, F, Moura, C S, Vieira, J, Teixeira, M R, Esteller, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031636/
https://www.ncbi.nlm.nih.gov/pubmed/23770855
http://dx.doi.org/10.1038/onc.2013.239

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