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Decreased hippocampal volume and increased anxiety in a transgenic mouse model expressing the human CYP2C19 gene
Selective serotonin reuptake inhibitors, tricyclic antidepressants, various psychoactive drugs, as well as endogenous steroids and cannabinoid-like compounds are metabolized by the polymorphic cytochrome P450 2C19 (CYP2C19). Absence of this enzyme has been recently shown to associate with lower leve...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031638/ https://www.ncbi.nlm.nih.gov/pubmed/23877834 http://dx.doi.org/10.1038/mp.2013.89 |