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Decreased hippocampal volume and increased anxiety in a transgenic mouse model expressing the human CYP2C19 gene

Selective serotonin reuptake inhibitors, tricyclic antidepressants, various psychoactive drugs, as well as endogenous steroids and cannabinoid-like compounds are metabolized by the polymorphic cytochrome P450 2C19 (CYP2C19). Absence of this enzyme has been recently shown to associate with lower leve...

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Detalles Bibliográficos
Autores principales:	Persson, A, Sim, S C, Virding, S, Onishchenko, N, Schulte, G, Ingelman-Sundberg, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031638/ https://www.ncbi.nlm.nih.gov/pubmed/23877834 http://dx.doi.org/10.1038/mp.2013.89

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