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A Dangerous Duo in Adipose Tissue: High-Mobility Group Box 1 Protein and Macrophages
High-mobility group box 1 (HMGB1) protein first made headlines 40 years ago as a non-histone nuclear protein that regulates gene expression. Not so long ago, it was also shown that HMGB1 has an additional surprising function. When released into the extracellular milieu, HMGB1 triggers an inflammator...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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YJBM
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031786/ https://www.ncbi.nlm.nih.gov/pubmed/24910558 |