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Examination of Structure–Activity Relationship of Viologen-Based Dendrimers as CXCR4 Antagonists and Gene Carriers

[Image: see text] Chemokine receptors and their ligands play a central role in cancer metastasis, inflammatory disorders, and viral infections. Viologen dendrimers (VGD) emerged recently as a promising class of synthetic polycationic ligands for chemokine receptor CXCR4. The objective of this study...

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Detalles Bibliográficos
Autores principales: Li, Jing, Lepadatu, Ana-Maria, Zhu, Yu, Ciobanu, Marius, Wang, Yan, Asaftei, Simona C., Oupický, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032196/
https://www.ncbi.nlm.nih.gov/pubmed/24821372
http://dx.doi.org/10.1021/bc500191q