Lead Optimization Studies of Cinnamic Amide EP2 Antagonists

[Image: see text] Prostanoid receptor EP2 can play a proinflammatory role, exacerbating disease pathology in a variety of central nervous system and peripheral diseases. A highly selective EP2 antagonist could be useful as a drug to mitigate the inflammatory consequences of EP2 activation. We recent...

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Detalles Bibliográficos
Autores principales: Ganesh, Thota, Jiang, Jianxiong, Yang, Myung-Soon, Dingledine, Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032197/
https://www.ncbi.nlm.nih.gov/pubmed/24773616
http://dx.doi.org/10.1021/jm5000672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032197/
https://www.ncbi.nlm.nih.gov/pubmed/24773616
http://dx.doi.org/10.1021/jm5000672

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